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Teresa Binstock
Researcher in Developmental & Behavioral Neuroanatomy
March 18, 2009
Dear Senator Grassley,
An FDA document (1) provides evidence that in most, indeed in nearly all pre-market testing of Gardasil, aluminum compounds that were in the vaccine and vaccinations were also in the placebo injections. As an autism-parent summarized: "...in the double blind trials on Gardasil, they had aluminum in the placebo as well as the HPV vax."
Although a Merck employee's review states that aluminum adjuvants are safe (7), other researchers state differently, eg, "Among the vaccine's potentially toxic components are the adjuvants aluminum hydroxide..." (8). Furthermore, aluminum is increasingly implicated in neurodegeneration (eg, 9-12).
These several findings suggest that Merck's testing was deliberately designed to neutralize adverse effects from aluminum injections, particularly in the context of vaccination-reactions. As of this morning, EnvironmentalHealthNews (EHN) had 61 articles about Gardasil. Many news articles focus upon one or more individual's adverse reactions to Gardasil, and the total number of Gardasil-induced adversities continues to increase (eg, 13).
That aluminum compounds were allowed to be included in placebo injections and in Gardasil injections nullifies the findings which prompted FDA approval (1). This issue merits attention by EHN and other organizations concerned with vaccination policy and vaccination safety. Further insights into this Merck-FDA abuse of science can be found in several blogs (eg, 2-5).
Although I personally am not entirely anti-vaccine and am very much for vaccinations to be proven safe and for vaccination schedules to be proven safe, I am astounded that Merck was allowed to include aluminum compounds in the placebo. Junk science at its profitable best.
Teresa Binstock
Researcher in Developmental & Behavioral Neuroanatomy
P.O. Box 1788
Estes Park CO 80517
usa
1. Clinical Review of Biologics License Application for Human Papillomavirus
6, 11, 16, 18 L1 Virus Like Particle Vaccine (S. cerevisiae)
(STN 125126 GARDASIL), manufactured by Merck, Inc.
http://www.fda.gov/cber/review/hpvmer060806r.pdf
2. Gardasil clinical trials -- Placebo www.renewamerica.us/columns/janak/080723
by Cynthia Janak cj1951@ameritech.net;
3. The great Gardasil vaccine cover-up www.renewamerica.us/columns/janak/070227
4. Gardasil Vaccine Not Proven Safe www.cogforlife.org/gardasilNVIC.htm
5. [PDF] NVIC SAYS GARDASIL (anti cancer vaccine) NOT PROVEN SAFE www.taxtyranny.ca/images/HTML/Vaccines/Articles/NotProven.pdf
6. en.wikipedia.org/wiki/Immunologic_adjuvant
7. Aluminum compounds as vaccine adjuvants.
Gupta RK.
Wyeth-Lederle Vaccines and Pediatrics, 401 North Middletown Road, Pearl River, NY 10965, USA
Adv Drug Deliv Rev. 1998 Jul 6;32(3):155-172. PMID: 10837642
8. Aluminum adjuvant linked to Gulf War illness induces motor neuron death in mice.
Petrik MS et al. Neuromolecular Med. 2007;9(1):83-100. PMID: 17114826
from the abstract: ...Behavioral testing showed motor deficits in the aluminum treatment group that expressed as a progressive decrease in strength measured by the wire-mesh hang test (final deficit at 24 wk; about 50%). Significant cognitive deficits in water-maze learning were observed in the combined aluminum and squalene group (4.3 errors per trial) compared with the controls (0.2 errors per trial) after 20 wk. Apoptotic neurons were identified in aluminum-injected animals that showed significantly increased activated caspase-3 labeling in lumbar spinal cord (255%) and primary motor cortex (192%) compared with the controls. Aluminum-treated groups also showed significant motor neuron loss (35%) and increased numbers of astrocytes (350%) in the lumbar spinal cord. The findings suggest a possible role for the aluminum adjuvant in some neurological features associated with GWI and possibly an additional role for the combination of adjuvants.
9: Blood-brain barrier flux of aluminum, manganese, iron and other metals suspected to contribute to metal-induced neurodegeneration.
Yokel RA. J Alzheimers Dis. 2006 Nov;10(2-3):223-53. Review.
10: Aluminum complexing enhances amyloid beta protein penetration of blood-brain barrier.
Banks WA, Niehoff ML, Drago D, Zatta P. Brain Res. 2006 Oct 20;1116(1):215-21. Epub 2006 Aug 30.
11: Some aspects of astroglial functions and aluminum implications for neurodegeneration.
Aremu DA, Meshitsuka S. Brain Res Rev. 2006 Aug 30;52(1):193-200.
12: Nanomolar aluminum induces pro-inflammatory and pro-apoptotic gene expression in human brain cells in primary culture.
Lukiw WJ, Percy ME, Kruck TP. J Inorg Biochem. 2005 Sep;99(9):1895-8.
13. Gardasil Adverse Events Include Deaths, Seizures, Judicial Watch Says
There have been 3461 reports of adverse events, including a maximum of 11 deaths, in patients receiving Merck’s cervical cancer vaccine Gardasil, ...
http://www.fdanews.com/newsletter/article?articleId=99624&issueId=10844
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